If a pinch hitter or pinch runner is substituted for a DH, what must occur?

When a designated hitter (DH) is substituted for by a pinch hitter or pinch runner, the original DH must exit the game entirely. This rule is in place to maintain the integrity of the DH role, which is specifically designed for one player to bat in place of a designated fielder. Once a substitute is made for the DH, the original player cannot return to the game, ensuring that the substitution is clear and maintains the structure of the lineup.

This prevents any confusion regarding who is eligible to bat for the team and keeps the game organized. By requiring the original DH to leave the game, it ensures that the substitution is definitive and that the integrity of the gameplay is upheld. The other options suggest scenarios that would allow for continued participation of the original DH, which contradicts this rule and could lead to violations of standard play protocols.